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SOS1 Rekombinanter Antikörper

SOS1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2J16

Kat-Nr. : 82784-2-PBS

Synonyme

2J16, Son of sevenless homolog 1, SOS 1, SOS-1

Filter:
  • Western Blot (WB) analysis of various lysates using SOS1 Recombinant antibody (82784-2-RR)

    WB analysis using 82784-2-RR (same clone as 82784-2-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 82784-2-RR (SOS1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 82784-2-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

82784-2-PBS bindet in WB, Indirect ELISA SOS1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen Peptid
Vollständiger Name son of sevenless homolog 1 (Drosophila)
Berechnetes Molekulargewicht 152 kDa
Beobachtetes Molekulargewicht 170 kDa
GenBank-ZugangsnummerNM_005633
Gene symbol SOS1
Gene ID (NCBI) 6654
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SOS1 promotes the exchange of Ras-bound GDP by GTP. EPS8, E3B1 and SOS1 form a tricomplex in vivo that exhibits RAC-specific guanine nucleotide exchange factor activity in vitro. Defects in SOS1 are the cause of gingival fibromatosis 1 (GGF1). Defects in SOS1 are the cause of Noonan syndrome type 4 (NS4). The antibody is specific to SOS1.