SOSTDC1 Polyklonaler Antikörper

SOSTDC1 Polyklonal Antikörper für WB, IF/ICC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22213-1-AP

Synonyme

CDA019, Ectodermal BMP inhibitor, ECTODIN, sclerostin domain containing 1, SOSTDC1, USAG 1, USAG1

---

• 

  WB analysis using 22213-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 22213-1-AP (SOSTDC1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours.

• 

  IF Staining of Saos-2 using 22213-1-AP

  Immunofluorescent analysis of (-20°C Methanol) fixed Saos-2 cells using SOSTDC1 antibody (22213-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L).

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: human milk
• Erfolgreiche Detektion in IF/ICC: Saos-2 cells

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:2000
• Immunfluoreszenz (IF)/ICC: IF/ICC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

22213-1-AP bindet in WB, IF/ICC, ELISA SOSTDC1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: SOSTDC1 fusion protein Ag17538
• Vollständiger Name: sclerostin domain containing 1
• Berechnetes Molekulargewicht: 206 aa, 23 kDa
• Beobachtetes Molekulargewicht: 23-26 kDa
• GenBank-Zugangsnummer: BC008484
• Gene symbol: SOSTDC1
• Gene ID (NCBI): 25928
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SOSTDC1 (Sclerostin domain-containing protein 1), also known as Ectodin (Ectodermal BMP inhibitor), is a member of the sclerostin family. It is an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain and is highly abundant in milk and kidney. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death.