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SOSTDC1 Polyklonaler Antikörper

SOSTDC1 Polyklonal Antikörper für WB, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22213-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using SOSTDC1 Polyclonal antibody (22213-1-AP)

    WB analysis using 22213-1-AP (same clone as 22213-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 22213-1-AP (SOSTDC1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 22213-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of Saos-2 cells using SOSTDC1 Polyclonal antibody (22213-1-AP)

    IF Staining of Saos-2 using 22213-1-AP (same clone as 22213-1-PBS)

    Immunofluorescent analysis of (-20°C Methanol) fixed Saos-2 cells using SOSTDC1 antibody (22213-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 22213-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

22213-1-PBS bindet in WB, IF/ICC, Indirect ELISA SOSTDC1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SOSTDC1 fusion protein Ag17538
Vollständiger Name sclerostin domain containing 1
Berechnetes Molekulargewicht 206 aa, 23 kDa
Beobachtetes Molekulargewicht 23-26 kDa
GenBank-ZugangsnummerBC008484
Gene symbol SOSTDC1
Gene ID (NCBI) 25928
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SOSTDC1 (Sclerostin domain-containing protein 1), also known as Ectodin (Ectodermal BMP inhibitor), is a member of the sclerostin family. It is an N-glycosylated, secreted protein with a C-terminal cystine knot-like domain and is highly abundant in milk and kidney. This protein functions as a bone morphogenetic protein (BMP) antagonist. Specifically, it directly associates with BMPs, prohibiting them from binding their receptors, thereby regulating BMP signaling during cellular proliferation, differentiation, and programmed cell death.