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SOX14 Polyklonaler Antikörper

SOX14 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30613-1-PBS

Synonyme

SOX28

Filter:
  • Western Blot (WB) analysis of various lysates using SOX14 Polyclonal antibody (30613-1-AP)

    WB analysis using 30613-1-AP (same clone as 30613-1-PBS)

    Mouse brain tissue were subjected to SDS PAGE followed by western blot with 30613-1-AP (SOX14 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30613-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30613-1-PBS bindet in WB, Indirect ELISA SOX14 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SOX14 fusion protein Ag31127
Vollständiger Name SRY (sex determining region Y)-box 14
Berechnetes Molekulargewicht 240 aa, 26 kDa
Beobachtetes Molekulargewicht26 kDa
GenBank-ZugangsnummerBC106730
Gene symbol SOX14
Gene ID (NCBI) 8403
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SOX14, also known as SOX28, is a member of the SOX (SRY-related HMG-box) family of transcription factors. This intronless gene encodes a protein that acts as a transcriptional regulator after forming complexes with other proteins. It is involved in embryonic development and cell fate determination. SOX14 is primarily expressed in the nervous system, where it plays a role in neuronal differentiation and circuit formation. Mutations in SOX14 are suggested to be responsible for limb defects associated with conditions such as blepharophimosis, ptosis, epicanthus inversus syndrome (BPES), and Moebius syndrome. Additionally, SOX14 has been implicated in tumor development, with studies indicating its involvement in cervical cancer through mechanisms such as the p53 and Wnt/β-catenin pathways. (PMID: 34098886, PMID: 34181293)