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SOX17 Polyklonaler Antikörper

SOX17 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24903-1-PBS

Synonyme

Transcription factor SOX-17, Transcription factor SOX 17

Filter:
  • Western Blot (WB) analysis of various lysates using SOX17 Polyclonal antibody (24903-1-AP)

    WB analysis using 24903-1-AP (same clone as 24903-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 24903-1-AP (SOX17 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24903-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of PC-3 cells using SOX17 Polyclonal antibody (24903-1-AP)

    WB analysis of PC-3 using 24903-1-AP (same clone as 24903-1-PBS)

    PC-3 cells were subjected to SDS PAGE followed by western blot with 24903-1-AP (SOX17 Antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 24903-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

24903-1-PBS bindet in WB, Indirect ELISA SOX17 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SOX17 fusion protein Ag19157
Vollständiger Name SRY (sex determining region Y)-box 17
Berechnetes Molekulargewicht 414 aa, 44 kDa
Beobachtetes Molekulargewicht 44 kDa
GenBank-ZugangsnummerBC111365
Gene symbol SOX17
Gene ID (NCBI) 64321
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Transcription factor SOX 17 (SOX17) also named as SRY box 17 is a 414 amino acid protein, which contains one Sox C-terminal domain and one HMG box DNA-binding domain. SOX17 as a transcription regulator binds target promoter DNA and bend the DNA via WNT3A. SOX17 is a marker of endodermal cells and a transcriptional regulator containing a DNA binding domain called the HMG box. In mouse embryos, SOX17 plays critical roles in the growth and differentiation of definitive endodermal cells (PMID: 11973269), the remodeling of endothelial cells (PMID: 16895970), hindgut endoderm expansion with localization of primordial germ cells (PMID: 19371732), and gallbladder/bile duct formation (PMID: 19913509).