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SPCS3 Polyklonaler Antikörper

SPCS3 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17640-1-PBS

Synonyme

PRO3567, SPase 22/23 kDa subunit, SPC22, SPC22/23, SPC3

Filter:
  • Western Blot (WB) analysis of various lysates using SPCS3 Polyclonal antibody (17640-1-AP)

    WB analysis using 17640-1-AP (same clone as 17640-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17640-1-AP (SPCS3 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17640-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using SPCS3 Polyclonal antibody (17640-1-AP)

    WB analysis using 17640-1-AP (same clone as 17640-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17640-1-AP (SPCS3 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17640-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of rat liver tissue using SPCS3 Polyclonal antibody (17640-1-AP)

    IHC staining of rat liver using 17640-1-AP (same clone as 17640-1-PBS)

    Immunohistochemical analysis of paraffin-embedded rat liver tissue slide using 17640-1-AP (SPCS3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17640-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human placenta tissue using SPCS3 Polyclonal antibody (17640-1-AP)

    IHC staining of human placenta using 17640-1-AP (same clone as 17640-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human placenta tissue slide using 17640-1-AP (SPCS3 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 17640-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17640-1-PBS bindet in WB, IHC, Indirect ELISA SPCS3 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SPCS3 fusion protein Ag11780
Vollständiger Name signal peptidase complex subunit 3 homolog (S. cerevisiae)
Berechnetes Molekulargewicht 180 aa, 20 kDa
Beobachtetes Molekulargewicht23 kDa
GenBank-ZugangsnummerBC047290
Gene symbol SPCS3
Gene ID (NCBI) 60559
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The microsomal signal peptidase complex (SPC), which is an essential membrane component in the endoplasmic reticulum (ER), has five subunits, including SEC11A, SEC11C, SPCS1, SPCS2, and SPCS3. Functionally, SPC removes signal peptides (SPs) from a series of secretory pre-proteins with high specificity. The dysregulation of the other SPC subunits was also observed in some tumors. SPCS3 expression can be used as a component of a risk score model to predict the survival of patients with pancreatic adenocarcinoma. (PMID: 35653344)