SPDYC Polyklonaler Antikörper

SPDYC Polyklonal Antikörper für IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 22471-1-PBS

Synonyme

---

• 

  IHC staining of human liver using 22471-1-AP (same clone as 22471-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 22471-1-AP (SPDYC antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22471-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human liver using 22471-1-AP (same clone as 22471-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 22471-1-AP (SPDYC antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22471-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 22471-1-AP (same clone as 22471-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 22471-1-AP (SPDYC antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22471-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 22471-1-AP (same clone as 22471-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney tissue slide using 22471-1-AP (SPDYC antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22471-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 22471-1-AP (same clone as 22471-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 22471-1-AP (SPDYC antibody) at dilution of 1:500 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22471-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human lung cancer using 22471-1-AP (same clone as 22471-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 22471-1-AP (SPDYC antibody) at dilution of 1:500 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 22471-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

22471-1-PBS bindet in IHC, Indirect ELISA SPDYC und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: SPDYC fusion protein Ag18126
• Vollständiger Name: speedy homolog C (Xenopus laevis)
• Berechnetes Molekulargewicht: 293 aa, 33 kDa
• Beobachtetes Molekulargewicht: 33-40 kDa
• GenBank-Zugangsnummer: BC137244
• Gene symbol: SPDYC
• Gene ID (NCBI): 387778
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-affinitätsgereinigt
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SPDYC(Speedy protein C), also known as RINGOC and Ringo2, promotes progression through the cell cycle via binding and activation of CDK1 and CDK2. Downregulation of SPDYC inhibits cell growth, reduces the fraction of cells in G1, and increases the S and G2 populations(PMID: 18802405). SPDYC is involved in the spindle-assembly checkpoint and required for recruitment of MAD2L1, BUBR1 and BUB1 to kinetochores(Uniprot).