SPHK1 Rekombinanter Antikörper

SPHK1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241017A6

Kat-Nr. : 84640-1-PBS

Synonyme

241017A6, Acetyltransferase SPHK1, EC:2.3.1.-, EC:2.7.1.91, SK1

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  WB analysis of THP-1 using 84640-1-RR (same clone as 84640-1-PBS)

  THP-1 cells were subjected to SDS PAGE followed by western blot with 84640-1-RR (SPHK1 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84640-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

84640-1-PBS bindet in WB, Indirect ELISA SPHK1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: sphingosine kinase 1
• Berechnetes Molekulargewicht: 51 kDa
• Beobachtetes Molekulargewicht: 42 kDa
• GenBank-Zugangsnummer: NM_182965
• Gene symbol: SPHK1
• Gene ID (NCBI): 8877
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SPHK(Sphingosine kinase 1) is also named as SPHK, SPK.It catalyzes the phosphorylation of sphingosine to form sphingosine 1-phosphate (SPP), a lipid mediator with both intra- and extracellular functions and is precariously perched at the balance point between progrowth and pro-death signalling in the cell.Endogenous SPHK1 purified from placenta has identical enzymatic characteristics, suggesting posttranslational modification does not effect functional properties(PMID:10947957).It has 2 isoforms produced by alternative splicing and can form the oligomeric structure(PMID:22335554).