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SPIRE1 Polyklonaler Antikörper

SPIRE1 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 11295-1-PBS

Synonyme

KIAA1135, Protein spire homolog 1, Spir 1, SPIR1, Spir-1

Filter:
  • Western Blot (WB) analysis of various lysates using SPIRE1 Polyclonal antibody (11295-1-AP)

    WB analysis using 11295-1-AP (same clone as 11295-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 11295-1-AP (SPIRE1 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 11295-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human lung cancer tissue using SPIRE1 Polyclonal antibody (11295-1-AP)

    IHC staining of human lung cancer using 11295-1-AP (same clone as 11295-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 11295-1-AP (SPIRE1 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with . This data was developed using the same antibody clone with 11295-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human lung cancer tissue using SPIRE1 Polyclonal antibody (11295-1-AP)

    IHC staining of human lung cancer using 11295-1-AP (same clone as 11295-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human lung cancer tissue slide using 11295-1-AP (SPIRE1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with . This data was developed using the same antibody clone with 11295-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse stomach tissue using SPIRE1 Polyclonal antibody (11295-1-AP)

    IHC staining of mouse stomach using 11295-1-AP (same clone as 11295-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse stomach tissue slide using 11295-1-AP (SPIRE1 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 11295-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

11295-1-PBS bindet in WB, IHC, Indirect ELISA SPIRE1 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SPIRE1 fusion protein Ag1798
Vollständiger Name spire homolog 1 (Drosophila)
Berechnetes Molekulargewicht 64 kDa
Beobachtetes Molekulargewicht50-60 kDa, 95 kDa
GenBank-ZugangsnummerBC016825
Gene symbol SPIRE1
Gene ID (NCBI) 56907
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SPIRE1, Protein spire homolog 1, belongs to the family of Wiskott-Aldrich homology region-2 (WH2) proteins (PMID: 11747823). SPIRE1 acts as an actin nucleation factor, associated with the slow-growing pointed end of the new filament (PMID: 11747823, PMID: 21620703). SPIRE1 and FMN2 promote assembly of nuclear actin filaments in response to DNA damage in order to facilitate movement of chromatin and repair factors after DNA damage (PMID: 26287480).