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SPOPL Polyklonaler Antikörper

SPOPL Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 17740-1-PBS

Synonyme

HIB homolog 2, Roadkill homolog 2, speckle type POZ protein like, Speckle-type POZ protein-like

Filter:
  • Western Blot (WB) analysis of various lysates using SPOPL Polyclonal antibody (17740-1-AP)

    WB analysis using 17740-1-AP (same clone as 17740-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 17740-1-AP (SPOPL antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 17740-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

17740-1-PBS bindet in WB, Indirect ELISA SPOPL und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SPOPL fusion protein Ag11951
Vollständiger Name speckle-type POZ protein-like
Berechnetes Molekulargewicht 392 aa, 45 kDa
Beobachtetes Molekulargewicht 39-45 kDa
GenBank-ZugangsnummerBC071613
Gene symbol SPOPL
Gene ID (NCBI) 339745
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Speckle Type POZ Protein Like (SPOPL), a member of the MATH-BTB protein family, was frst identifed in 2010 with 82.6% sequence homology with Speckle-type POZ protein (SPOP). SPOPL is an E3 ubiquitin ligase protein that ubiquitinates and degrades the target protein. SPOPL can be used as a potential prognostic biomarker for glioblastoma multiforme in clinical work and promotes the proliferation and stemness of glioma stem cells by activating the Notch signaling pathway (PMID:37523046).