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SPP2 Polyklonaler Antikörper

SPP2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 30922-1-PBS

Synonyme

SPP24, Spp 24, Secreted phosphoprotein 24, Secreted phosphoprotein 2

Filter:
  • Western Blot (WB) analysis of various lysates using SPP2 Polyclonal antibody (30922-1-AP)

    WB analysis using 30922-1-AP (same clone as 30922-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 30922-1-AP (SPP2 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 30922-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

30922-1-PBS bindet in WB, Indirect ELISA SPP2 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SPP2 fusion protein Ag29299
Vollständiger Name secreted phosphoprotein 2, 24kDa
Berechnetes Molekulargewicht 24 kDa
Beobachtetes Molekulargewicht24 kDa
GenBank-ZugangsnummerNM_006944
Gene symbol SPP2
Gene ID (NCBI) 6694
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SPP2 (Secreted phosphoprotein 24), also known as SPP24. SPP2 is a secreted phosphoprotein, which was originally isolated and purified from bovine bone density. It is widely distributed in the body, mainly produced in the liver and transported to other tissues. SPP2 is expressed in many tissues, especially in the liver. Studies have shown that the expression level of SPP2 is up-regulated in liver cirrhosis. In addition, the expression of SPP2 is significantly related to many genes, including APOA1, SLC2A2 and TTR (PMID: 38448371). SPP2 has many biological functions, including: it can inhibit the activity of cysteine protease, participate in bone formation, inhibit calcification, and regulate BMP/TGF-β signaling pathway. SPP2 may be a tumor suppressor, which inhibits the development of HCC by inhibiting BMP/TGF-β signaling pathway. The molecular weight of SPP2 is 24 kDa.