SPPL2A Polyklonaler Antikörper

SPPL2A Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13255-1-PBS

Synonyme

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  WB analysis of human colon using 13255-1-AP (same clone as 13255-1-PBS)

  human colon tissue were subjected to SDS PAGE followed by western blot with 13255-1-AP (SPPL2A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  WB analysis of Jurkat using 13255-1-AP (same clone as 13255-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 13255-1-AP (SPPL2A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  WB analysis of Jurkat using 13255-1-AP (same clone as 13255-1-PBS)

  Jurkat cells were subjected to SDS PAGE followed by western blot with 13255-1-AP (SPPL2A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse colon using 13255-1-AP (same clone as 13255-1-PBS)

  mouse colon tissue were subjected to SDS PAGE followed by western blot with 13255-1-AP (SPPL2A antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  WB analysis of human colon using 13255-1-AP (same clone as 13255-1-PBS)

  human colon tissue were subjected to SDS PAGE followed by western blot with 13255-1-AP (SPPL2A antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 13255-1-AP (same clone as 13255-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 13255-1-AP (SPPL2A antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 13255-1-AP (same clone as 13255-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 13255-1-AP (SPPL2A antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 13255-1-AP (same clone as 13255-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 13255-1-AP (SPPL2A antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 13255-1-AP (same clone as 13255-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 13255-1-AP (SPPL2A antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 13255-1-AP (same clone as 13255-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 13255-1-AP (SPPL2A antibody) at dilution of 1:50 (under 10x lens). This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human kidney using 13255-1-AP (same clone as 13255-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human kidney using 13255-1-AP (SPPL2A antibody) at dilution of 1:50 (under 40x lens). This data was developed using the same antibody clone with 13255-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

13255-1-PBS bindet in WB, IHC, Indirect ELISA SPPL2A und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: SPPL2A fusion protein Ag3935
• Vollständiger Name: signal peptide peptidase-like 2A
• Berechnetes Molekulargewicht: 520 aa, 58 kDa
• Beobachtetes Molekulargewicht: 58 kDa
• GenBank-Zugangsnummer: BC025740
• Gene symbol: SPPL2A
• Gene ID (NCBI): 84888
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SPPL2A(Signal peptide peptidase-like 2A) is also named as IMP3(Intramembrane protease 3), PSL2(Presenilin-like protein 2) and belongs to the peptidase A22B family. It is an aspartyl intramembrane protease, has been implicated in the proteolysis of TNF-alpha, Fas Ligand and Bri2 and endogenous signal-peptide-peptidase-like2A (SPPL2a) is localised in lysosomes/late endosomes(PMID:21896273). This protein has a signal peptide with 25 amino acid and seven glycosylation sites.