SPTBN1 Monoklonaler Antikörper

SPTBN1 Monoklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human, Kaninchen, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1E1D1

Kat-Nr. : 67978-1-PBS

Synonyme

Beta II spectrin, betaSpII, ELF, Fodrin beta chain, Spectrin beta chain, brain 1, SPTB2, SPTBN1

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  WB analysis using 67978-1-Ig (same clone as 67978-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67978-1-Ig (SPTBN1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67978-1-PBS in a different storage buffer formulation.

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  WB analysis of mouse cerebellum using 67978-1-Ig (same clone as 67978-1-PBS)

  mouse cerebellum tissue were subjected to SDS PAGE followed by western blot with 67978-1-Ig (SPTBN1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67978-1-PBS in a different storage buffer formulation.

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  IHC staining of human liver cancer using 67978-1-Ig (same clone as 67978-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human liver cancer tissue slide using 67978-1-Ig (SPTBN1 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 67978-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

67978-1-PBS bindet in WB, IHC, Indirect ELISA SPTBN1 und zeigt Reaktivität mit Hausschwein, human, Kaninchen, Maus, Ratten

• Getestete Reaktivität: Hausschwein, human, Kaninchen, Maus, Ratte
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: SPTBN1 fusion protein Ag31713
• Vollständiger Name: spectrin, beta, non-erythrocytic 1
• Berechnetes Molekulargewicht: 2364 aa, 275 kDa
• Beobachtetes Molekulargewicht: 250-275 kDa
• GenBank-Zugangsnummer: BC137282
• Gene symbol: SPTBN1
• Gene ID (NCBI): 6711
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SPTBN1 is the non-erythrocytic form of β-spectrin or β-fodrin. Spectrins are members of the superfamily of F-actin cross linking proteins that are important as scaffolding proteins for protein sorting, cell adhesion, and migration. Reduced expression of SPTBN1 has been found to correlate with shorter survival of patients with hepatocellular cancer, pancreatic cancer and other malignancies of the gastrointestinal tract, suggesting tumor suppression ability of this protein.