SPTLC2 Monoklonaler Antikörper

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• KD/KO Validated

SPTLC2 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

2G6A12

Kat-Nr. : 68094-1-PBS

Synonyme

KIAA0526, LCB 2, LCB2, LCB2a, Serine palmitoyltransferase 2, SPT 2, SPT2, SPTLC2

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  WB analysis using 68094-1-Ig (same clone as 68094-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 68094-1-Ig (SPTLC2 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. The membrane was stripped and reblotted with HRP-conjugated Beta Actin Monoclonal antibody (HRP-66009) as loading control. This data was developed using the same antibody clone with 68094-1-PBS in a different storage buffer formulation.

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  WB analysis of HEK-293 using 68094-1-Ig (same clone as 68094-1-PBS)

  WB result of SPTLC2 antibody (68094-1-Ig; 1:3000; incubated at room temperature for 1.5 hours) with sh-Control and sh-SPTLC2 transfected HEK-293 cells. This data was developed using the same antibody clone with 68094-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

68094-1-PBS bindet in WB, Indirect ELISA SPTLC2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: SPTLC2 fusion protein Ag28380
• Vollständiger Name: serine palmitoyltransferase, long chain base subunit 2
• Berechnetes Molekulargewicht: 63 kDa
• Beobachtetes Molekulargewicht: 60 kDa
• GenBank-Zugangsnummer: BC005123
• Gene symbol: SPTLC2
• Gene ID (NCBI): 9517
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Serine palmitoyltransferase long chain base subunit 2 (SPTLC2) is one of the subunits of the heterodimeric molecule Serine palmitoyltransferase (SPT). Sptlc2 deficiency not only affected T cell sphingolipid anabolism but also led to prolonged activation of the mechanistic target of rapamycin complex 1 (PMID: 30952607).