IL-1RL1/ST2 Monoklonaler Antikörper

IL-1RL1/ST2 Monoklonal Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

Hausschwein, human, Maus, Ratte

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

7A2A7

Kat-Nr. : 60112-1-PBS

Synonyme

IL1RL1, 7A2A7, DER4, EC:3.2.2.6, FIT 1

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  WB analysis using 60112-1-Ig (same clone as 60112-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60112-1-Ig (ST2 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60112-1-PBS in a different storage buffer formulation.

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  WB analysis of HEK-293 using 60112-1-Ig (same clone as 60112-1-PBS)

  HEK-293 cells were subjected to SDS PAGE followed by western blot with 60112-1-Ig (ST2 antibody at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60112-1-PBS in a different storage buffer formulation.

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  WB analysis of fetal human brain using 60112-1-Ig (same clone as 60112-1-PBS)

  fetal human brain tissue were subjected to SDS PAGE followed by western blot with 60112-1-Ig (ST2 antibody at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60112-1-PBS in a different storage buffer formulation.

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  WB analysis of SGC-7901 using 60112-1-Ig (same clone as 60112-1-PBS)

  SGC-7901 cells were subjected to SDS PAGE followed by western blot with 60112-1-Ig (ST2 antibody at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60112-1-PBS in a different storage buffer formulation.

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  WB analysis of pig brain using 60112-1-Ig (same clone as 60112-1-PBS)

  pig brain tissue were subjected to SDS PAGE followed by western blot with 60112-1-Ig (ST2 antibody at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60112-1-PBS in a different storage buffer formulation.

• 

  WB analysis of mouse brain using 60112-1-Ig (same clone as 60112-1-PBS)

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 60112-1-Ig (ST2 antibody at dilution of 1:8000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60112-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

60112-1-PBS bindet in WB, ELISA IL-1RL1/ST2 und zeigt Reaktivität mit Hausschwein, human, Maus, Ratten

• Getestete Reaktivität: Hausschwein, human, Maus, Ratte
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: IL-1RL1/ST2 fusion protein Ag2555
• Vollständiger Name: interleukin 1 receptor-like 1
• Berechnetes Molekulargewicht: 63 kDa, 37 kDa, 30 kDa
• Beobachtetes Molekulargewicht: 63 kDa
• GenBank-Zugangsnummer: BC030975
• Gene symbol: IL1RL1
• Gene ID (NCBI): 9173
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ST2, also known as IL1RL1, is a member of the IL-1 superfamily and serves as the receptor for IL-33. It plays a major role in immune and inflammatory responses. ST2 is expressed by various types of immune cells including Th2 cells, mast cells, type 2 innate lymphoid cells, eosinophils, basophils, NK cells, and non-immune cells, including cardiomyocytes. Two forms of ST2 exist: a membrane-bound form and a soluble form (sST2). The membrane-bound form activates the MyD88/NF-κB signaling pathway to enhance mast cell, Th2, regulatory T cell (Treg), and innate lymphoid cell type 2 functions. sST2 acts as a decoy receptor. (PMID: 27055914; 23999434; 28484466)