• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

STAT3 Polyklonaler Antikörper

STAT3 Polyklonal Antikörper für ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 10025-2-AP

Synonyme

Acute phase response factor, APRF, HIES, STAT3

Galerie der Validierungsdaten

Filter:
  • Western Blot (WB) analysis of HEK-293 cells using STAT3 Polyclonal antibody (10025-2-AP)

    WB analysis of HEK-293 using 10025-2-AP

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 10025-2-AP (STAT3 antibody) at dilution of 1:0 incubated at room temperature for 1.5 hours.

  • Immunohistochemistry (IHC) staining of human lung cancer tissue using STAT3 Polyclonal antibody (10025-2-AP)

    IHC staining of human lung cancer using 10025-2-AP

    Immunohistochemical analysis of paraffin-embedded human lung cancer using 10025-2-AP (STAT3 antibody) at dilution of 1:50 (under 40x lens).

  • Immunohistochemistry (IHC) staining of human lung cancer tissue using STAT3 Polyclonal antibody (10025-2-AP)

    IHC staining of human lung cancer using 10025-2-AP

    Immunohistochemical analysis of paraffin-embedded human lung cancer using 10025-2-AP (STAT3 antibody) at dilution of 1:50 (under 40x lens).

Geprüfte Anwendungen

Empfohlene Verdünnung

AnwendungVerdünnung
It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

10025-2-AP bindet in ELISA STAT3 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen STAT3 fusion protein Ag0018
Vollständiger Name signal transducer and activator of transcription 3 (acute-phase response factor)
Berechnetes Molekulargewicht 90-100 kDa
GenBank-ZugangsnummerBC014482
Gene symbol STAT3
Gene ID (NCBI) 6774
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
LagerungsbedingungenBei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Signal transducer and activator of transcription 3 (acute-phase response factor) (STAT3, synonyms: APRF, FLJ20882, MGC16063) is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT3 is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. STAT3 mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis. The small GTPase Rac1 has been shown to bind and regulate the activity of STAT3. This antibody is a rabbit polyclonal antibody raised against human STAT3 fusion protein.