• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0
  • Featured Product
  • KD/KO Validated

STAU1 Rekombinanter Antikörper

STAU1 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242179D12

Kat-Nr. : 84822-4-PBS

Synonyme

242179D12, Double-stranded RNA-binding protein Staufen homolog 1, STAU

Filter:
  • Western Blot (WB) analysis of various lysates using STAU1 Recombinant antibody (84822-4-RR)

    WB analysis using 84822-4-RR (same clone as 84822-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84822-4-RR (STAU1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84822-4-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HepG2 cells using STAU1 Recombinant antibody (84822-4-RR)

    WB analysis of HepG2 using 84822-4-RR (same clone as 84822-4-PBS)

    WB result of STAU1 antibody (84822-4-RR; 1:1000; incubated at room temperature for 1.5 hours) with sh-Control and sh-STAU1 transfected HepG2 cells. This data was developed using the same antibody clone with 84822-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84822-4-RR

    Affinity and Kinetic Characterization of 84822-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84822-4-RR against Human STAU1 were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

84822-4-PBS bindet in WB, Indirect ELISA STAU1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen STAU1 fusion protein Ag5464
Vollständiger Name staufen, RNA binding protein, homolog 1 (Drosophila)
Berechnetes Molekulargewicht 63 kDa
Beobachtetes Molekulargewicht55-65 kDa
GenBank-ZugangsnummerBC050432
Gene symbol STAU1
Gene ID (NCBI) 6780
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Staufen1 (STAU1)-mediated mRNA decay (SMD) degrades translationally active mRNAs that bind the double-stranded (ds)RNA binding protein STAU1 within their 3'-untranslated regions (3'UTRs) [PMID:21307942]. STAU1 can binds to stem structures and protect Dvl2 mRNA from degradation by associating with the secondary structure in the U1 region which is located at 5′ position of second U stretch in the U2 region [PMID:17510634]. It has a role in specific positioning of mRNAs at given sites in the cell by cross-linking cytoskeletal and RNA components, and in stimulating their translation at the site.