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STK39 Polyklonaler Antikörper

STK39 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 31064-1-PBS

Synonyme

DCHT, PASK, SPAK, Ste 20 related kinase

Filter:
  • Western Blot (WB) analysis of various lysates using STK39 Polyclonal antibody (31064-1-AP)

    WB analysis using 31064-1-AP (same clone as 31064-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 31064-1-AP (STK39 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 31064-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

31064-1-PBS bindet in WB, Indirect ELISA STK39 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen STK39 fusion protein Ag34503
Vollständiger Name serine threonine kinase 39 (STE20/SPS1 homolog, yeast)
Berechnetes Molekulargewicht59 kDa
Beobachtetes Molekulargewicht68 kDa
GenBank-ZugangsnummerBC166614
Gene symbol STK39
Gene ID (NCBI) 27347
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

STK39 (Serine/Threonine Kinase 39) is a proline- and alanine-rich Ste20-related kinase (also named as SPAK), which is composed of a short N-terminal proline and alanine repeats (PAPA box), a kinase catalytic domain and a C-terminal regulatory domain (PMID: 16382158). In mammalians, STK39 plays an important role in ion homeostasis by regulating the cation chloride cotransporters' activities, which is crucial for the modulation of renal salt transport and blood pressure (PMID: 33500714). Notably, STK39 is also implicated in the regulation of tumor cell proliferation, migration, and invasion in multiple cancers, including osteosarcoma and cervical cancer (PMID: 34335956).