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STXBP1 Polyklonaler Antikörper

STXBP1 Polyklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 20562-1-PBS

Synonyme

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  • Western Blot (WB) analysis of various lysates using STXBP1 Polyclonal antibody (20562-1-AP)

    WB analysis using 20562-1-AP (same clone as 20562-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 20562-1-AP (STXBP1 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20562-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human brain tissue using STXBP1 Polyclonal antibody (20562-1-AP)

    IHC staining of human brain using 20562-1-AP (same clone as 20562-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain using 20562-1-AP (STXBP1 antibody) at dilution of 1:100 (under 10x lens). This data was developed using the same antibody clone with 20562-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human brain tissue using STXBP1 Polyclonal antibody (20562-1-AP)

    IHC staining of human brain using 20562-1-AP (same clone as 20562-1-PBS)

    Immunohistochemical analysis of paraffin-embedded human brain using 20562-1-AP (STXBP1 antibody) at dilution of 1:100 (under 40x lens). This data was developed using the same antibody clone with 20562-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using STXBP1 Polyclonal antibody (20562-1-AP)

    IF Staining of HeLa using 20562-1-AP (same clone as 20562-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using STXBP1 antibody (20562-1-AP) at dilution of 1:50 and CoraLite594-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 20562-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

20562-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA STXBP1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Peptid
Vollständiger Name syntaxin binding protein 1
Berechnetes Molekulargewicht 68 kDa
Beobachtetes Molekulargewicht68 kDa
GenBank-ZugangsnummerNM_003165
Gene symbol STXBP1
Gene ID (NCBI) 6812
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

STXBP1, also named as UNC18A, N-Sec1 and p67 belongs to the STXBP/unc-18/SEC1 family. STXBP1 may participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. It is essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. STXBP1 can interact with syntaxins 1, 2, and 3 but not syntaxin 4. It may play a role in determining the specificity of intracellular fusion reactions. The antibody is specific to STXBP1.