SULT4A1 Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

SULT4A1 Polyklonal Antikörper für IP, WB,ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte und mehr (1)

Anwendung

WB, IP, IHC, IF

Konjugation

Unkonjugiert

Publikationen

15

Kat-Nr. : 12578-1-AP

Synonyme

BR STL 1, BRSTL1, hBR STL, hBR STL 1, NST, ST4A1, Sulfotransferase 4A1, SULT4A1, SULTX3

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Galerie der Validierungsdaten

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  WB analysis using 12578-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 12578-1-AP (SULT4A1 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

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  WB analysis of human brain using 12578-1-AP

  human brain tissue were subjected to SDS PAGE followed by western blot with 12578-1-AP (SULT4A1 antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours.

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  WB analysis of mouse brain using 12578-1-AP

  mouse brain tissue were subjected to SDS PAGE followed by western blot with 12578-1-AP (SULT4A1 Antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours.

• 

  IP experiment of mouse brain using 12578-1-AP

  IP Result of anti-SULT4A1 (IP:12578-1-AP, 4ug; Detection:12578-1-AP 1:300) with mouse brain tissue lysate 4000ug.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: Maushirngewebe, humanes Hirngewebe
• Erfolgreiche IP: Maushirngewebe

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:4000
• Immunpräzipitation (IP): IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 3 publications below
• WB: See 15 publications below
• IHC: See 3 publications below
• IF: See 4 publications below

Produktinformation

12578-1-AP bindet in WB, IP, IHC, IF SULT4A1 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• In Publikationen genannte Reaktivität: human, Maus, Ratte, Zebrafisch
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: SULT4A1 fusion protein Ag3271
• Vollständiger Name: sulfotransferase family 4A, member 1
• Berechnetes Molekulargewicht: 284 aa, 33 kDa
• Beobachtetes Molekulargewicht: 30-33 kDa
• GenBank-Zugangsnummer: BC022459
• Gene symbol: SULT4A1
• Gene ID (NCBI): 25830
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SULT4A1, also named as SULTX3, NST, ST4A1, hBR-STL and hBR-STL-1, belongs to the sulfotransferase 1 family. It may catalyze the sulfate conjugation of many drugs, xenobiotic compounds, hormones, and neurotransmitters. SULT4A1 displays activity towards L-triiodothyronine, thyroxine, estrone, p-nitrophenol, 2-naphtylamine, and 2-naphtol. It may have a role in the sulfation of drugs and neurotransmitters in the CNS. SULT4A1 is a brain-specific sulfotransferase believed to be involved in the metabolism of neurotransmitters. It is a novel cytosolic sulfotransferase that is primarily expressed in the brain.

Publikationen

Species	Application	Title
mouse,rat	WB,IF	J Neurosci; SULT4A1 Modulates Synaptic Development and Function by Promoting the Formation of PSD-95/NMDAR Complex.; Authors - Lorenza Culotta ; KD Validated
human,rat	WB,IHC	Biochem Pharmacol; Identification of metabolic pattern and bioactive form of resveratrol in human medulloblastoma cells.; Authors - Shu Xiao-Hong XH
mouse	WB	Mol Pharmacol; Regulation of mouse brain-selective sulfotransferase sult4a1 by cAMP response element-binding protein and activating transcription factor-2.; Authors - Butcher Neville J NJ
human	WB	FEBS J; Distinct sulfonation activities in resveratrol-sensitive and resveratrol-insensitive human glioblastoma cells.; Authors - Sun Zheng Z
	WB	Sci Rep; Sulfotransferase 4A1 activity facilitates sulfate-dependent cellular protection to oxidative stress.; Authors - Evan J Brettrager
human	WB,IHC,IF	PLoS One; Metabolic patterns and biotransformation activities of resveratrol in human glioblastoma cells: relevance with therapeutic efficacies.; Authors - Shu Xiao-Hong XH