• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

SUMO2/3 Polyklonaler Antikörper

SUMO2/3 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 10699-1-PBS

Synonyme

SUMO3, SUMO 3, SUMO 2, SMT3H1, SMT3A

Filter:
  • Western Blot (WB) analysis of various lysates using SUMO2/3 Polyclonal antibody (10699-1-AP)

    WB analysis using 10699-1-AP (same clone as 10699-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 10699-1-AP (SUMO2/3 antibody) at dilution of 1:800 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 10699-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

10699-1-PBS bindet in WB, Indirect ELISA SUMO2/3 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SUMO2/3 fusion protein Ag1135
Vollständiger Name SMT3 suppressor of mif two 3 homolog 3 (S. cerevisiae)
Berechnetes Molekulargewicht 12 kDa
Beobachtetes Molekulargewicht 11-20 kDa
GenBank-ZugangsnummerBC008420
Gene symbol SUMO3
Gene ID (NCBI) 6612
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Ubiquitin is most famous for its function in targeting proteins for degradation by the 26S proteasome, ubiquitin needs to be attached to a substrate in chains (polyubiquitylation) before being recognized by proteasome. Similarly, SUMO (small ubiquitin-related modifier) can be linked to substrates in chains (polysumoylation), SUMO modification has been implicated in many important cellular processes including the control of genome stability, signal transduction, targeting to and formation of nuclear compartments, cell cycle and meiosis. There are 4 confirmed SUMO isoforms in human, SUMO-1, SUMO-2, SUMO-3 and SUMO-4. SUMO-2 and SUMO-3 are nearly identical but are distinct from SUMO-1. SUMO2/3 conjugation was recently widely involved in neuroprotective activities. A substitution (M55V) of SUMO4 was strongly associated with the pathogenesis of type 1 diabetes (T1D) involving NF kappa B related mechanisms.