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SUR2/ABCC9 Polyklonaler Antikörper

SUR2/ABCC9 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 13599-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using SUR2/ABCC9 Polyclonal antibody (13599-1-AP)

    WB analysis using 13599-1-AP (same clone as 13599-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 13599-1-AP (SUR2/ABCC9 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13599-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using SUR2/ABCC9 Polyclonal antibody (13599-1-AP)

    WB analysis using 13599-1-AP (same clone as 13599-1-PBS)

    mouse heart were subjected to SDS PAGE followed by western blot with 13599-1-AP (SUR2/ABCC9 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 13599-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

13599-1-PBS bindet in WB, Indirect ELISA SUR2/ABCC9 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SUR2/ABCC9 fusion protein Ag4536
Vollständiger Name ATP-binding cassette, sub-family C (CFTR/MRP), member 9
Berechnetes Molekulargewicht 1549 aa, 174 kDa
Beobachtetes Molekulargewicht174 kDa
GenBank-ZugangsnummerBC033804
Gene symbol SUR2/ABCC9
Gene ID (NCBI) 10060
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

ABCC9, also known as SUR2, belongs to the ABC transporter superfamily. ABCC9 is a subunit of ATP-sensitive potassium channels (KATP), forming cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation (PMID: 9831708). ABCC9 is thought to form ATP-sensitive potassium channels in cardiac, skeletal, vascular, and non-vascular smooth muscle. Defects in ABCC9 cause dilated cardiomyopathy 10 and familial atrial fibrillation type 12 (ATFB12)(PMID: 15034580,17245405).