SCP3 Monoklonaler Antikörper

SCP3 Monoklonal Antikörper für WB, ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human und mehr (1)

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

Publikationen(1)

CloneNo.

1A11F1

Kat-Nr. : 66409-1-Ig

Synonyme

SYCP3, 1A11F1, COR1, SCP 3, SCP-3

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  WB analysis of human testis using 66409-1-Ig

  human testis tissue were subjected to SDS PAGE followed by western blot with 66409-1-Ig (SYCP3 Antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

• 

  WB analysis of DU 145 using 66409-1-Ig

  DU 145 cells were subjected to SDS PAGE followed by western blot with 66409-1-Ig (SYCP3 Antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: humanes Hodengewebe, DU 145-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:1000-1:8000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• WB: See 1 publications below
• IF: See 2 publications below

Produktinformation

66409-1-Ig bindet in WB, ELISA SCP3 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• In Publikationen genannte Reaktivität: Maus
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: SCP3 fusion protein Ag19330
• Vollständiger Name: synaptonemal complex protein 3
• Berechnetes Molekulargewicht: 236 aa, 28 kDa
• Beobachtetes Molekulargewicht: 30 kDa
• GenBank-Zugangsnummer: BC062662
• Gene symbol: SYCP3
• Gene ID (NCBI): 50511
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SYCP3 is an essential structural component of the synaptonemal complex. This complex is involved in synapsis, recombination and segregation of meiotic chromosomes. SYCP3 is required for centromere pairing during meiosis in male germ cells. SYCP3 is also required for normal meiosis during spermatogenesis and male fertility. Mutations in SYCP3 are associated with azoospermia in males and susceptibility to pregnancy loss in females.

Publikationen

Species	Application	Title
mouse	WB	Environ Pollut; Effects of polystyrene microparticles exposures on spermatogenic cell differentiation and reproductive endpoints in male mice; Authors - Rong Shen