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SYT2 Polyklonaler Antikörper

SYT2 Polyklonal Antikörper für WB, IF-P, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IF-P, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 21245-1-PBS

Synonyme

Synaptotagmin II, Synaptotagmin-2, SytII

Filter:
  • Western Blot (WB) analysis of various lysates using SYT2 Polyclonal antibody (21245-1-AP)

    WB analysis using 21245-1-AP (same clone as 21245-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21245-1-AP (SYT2 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21245-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of various lysates using SYT2 Polyclonal antibody (21245-1-AP)

    WB analysis using 21245-1-AP (same clone as 21245-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 21245-1-AP (SYT2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21245-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of mouse cerebellum tissue using SYT2 Polyclonal antibody (21245-1-AP)

    IF Staining of mouse cerebellum using 21245-1-AP (same clone as 21245-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse cerebellum tissue using SYT2 antibody (21245-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 21245-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of mouse cerebellum tissue using SYT2 Polyclonal antibody (21245-1-AP)

    IF Staining of mouse cerebellum using 21245-1-AP (same clone as 21245-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse cerebellum tissue using SYT2 antibody (21245-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 21245-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

21245-1-PBS bindet in WB, IF-P, Indirect ELISA SYT2 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen SYT2 fusion protein Ag15744
Vollständiger Name synaptotagmin II
Berechnetes Molekulargewicht 419 aa, 47 kDa
Beobachtetes Molekulargewicht70 kDa
GenBank-ZugangsnummerBC100815
Gene symbol SYT2
Gene ID (NCBI) 127833
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SYT2 (Synaptotagmin-2) a synaptic vesicle membrane protein, functions as a calcium sensor in vesicular trafficking and exocytosis. SYT2 is also plays a role in dendrite formation by melanocytes (PMID: 23999003). Mutations in SYT2 are associated with myasthenic syndrome, presynaptic, congenital, with or without motor neuropathy. SYT2 mutations cause a complex presynaptic congenital myasthenic syndrome (PMID: 26519543).