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SYTL4 Rekombinanter Antikörper

SYTL4 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

240556E2

Kat-Nr. : 83564-5-PBS

Synonyme

synaptotagmin like 4, SLP4, Granuphilin, Exophilin-2, Exophilin 2

Filter:
  • Western Blot (WB) analysis of various lysates using SYTL4 Recombinant antibody (83564-5-RR)

    WB analysis using 83564-5-RR (same clone as 83564-5-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 83564-5-RR (SYTL4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83564-5-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83564-5-RR

    Affinity and Kinetic Characterization of 83564-5-RR

    Biolayer interferometry (BLl) kinetic assays of 83564-5-RR against Human SYTL4 were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

83564-5-PBS bindet in WB, ELISA SYTL4 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen SYTL4 fusion protein Ag2772
Vollständiger Name synaptotagmin-like 4
Berechnetes Molekulargewicht 671 aa, 76 kDa
Beobachtetes Molekulargewicht74-76 kDa
GenBank-ZugangsnummerBC014913
Gene symbol SYTL4
Gene ID (NCBI) 94121
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SYTL4, also known as SLP4 or granuphilin, is a member of the synaptotagmin-like protein (Slp) family. Members of this family are characterized by presence of an N-terminal Slp homology domain (SHD), which functions as a Rab27-binding domain, and C-terminal tandem C2 domains, putative Ca(2+)-binding motifs. SYTL4 is specifically expressed on dense-core granules in certain neuroendocrine cells and negatively controls dense-core vesicle exocytosis through specific interaction with Rab27A. (PMID: 16481396; 16473610)