SYTL4 Rekombinanter Antikörper

SYTL4 Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

240556E2

Kat-Nr. : 83564-5-RR

Synonyme

synaptotagmin like 4, SLP4, Granuphilin, Exophilin-2, Exophilin 2

---

• 

  WB analysis using 83564-5-RR

  Various lysates were subjected to SDS PAGE followed by western blot with 83564-5-RR (SYTL4 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours.

• 

  Affinity and Kinetic Characterization of 83564-5-RR

  Biolayer interferometry (BLl) kinetic assays of 83564-5-RR against Human SYTL4 were performed. The affinity constant is below 1 pM.

---

Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: HeLa-Zellen, HEK-293-Zellen

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:500-1:3000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

83564-5-RR bindet in WB, ELISA SYTL4 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: SYTL4 fusion protein Ag2772
• Vollständiger Name: synaptotagmin-like 4
• Berechnetes Molekulargewicht: 671 aa, 76 kDa
• Beobachtetes Molekulargewicht: 74-76 kDa
• GenBank-Zugangsnummer: BC014913
• Gene symbol: SYTL4
• Gene ID (NCBI): 94121
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SYTL4, also known as SLP4 or granuphilin, is a member of the synaptotagmin-like protein (Slp) family. Members of this family are characterized by presence of an N-terminal Slp homology domain (SHD), which functions as a Rab27-binding domain, and C-terminal tandem C2 domains, putative Ca(2+)-binding motifs. SYTL4 is specifically expressed on dense-core granules in certain neuroendocrine cells and negatively controls dense-core vesicle exocytosis through specific interaction with Rab27A. (PMID: 16481396; 16473610)