SYTL5 Polyklonaler Antikörper

SYTL5 Polyklonal Antikörper für IHC, IF-P, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

IHC, IF-P, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 24528-1-PBS

Synonyme

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  IHC staining of mouse brain using 24528-1-AP (same clone as 24528-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 24528-1-AP (SYTL5 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24528-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse brain using 24528-1-AP (same clone as 24528-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 24528-1-AP (SYTL5 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24528-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat brain using 24528-1-AP (same clone as 24528-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 24528-1-AP (SYTL5 antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24528-1-PBS in a different storage buffer formulation.

• 

  IHC staining of rat brain using 24528-1-AP (same clone as 24528-1-PBS)

  Immunohistochemical analysis of paraffin-embedded rat brain tissue slide using 24528-1-AP (SYTL5 antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 24528-1-PBS in a different storage buffer formulation.

• 

  IF Staining of rat brain using 24528-1-AP (same clone as 24528-1-PBS)

  Immunofluorescent analysis of (4% PFA) fixed rat brain tissue using SYTL5 antibody (24528-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 24528-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

24528-1-PBS bindet in IHC, IF-P, Indirect ELISA SYTL5 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: SYTL5 fusion protein Ag21698
• Vollständiger Name: synaptotagmin-like 5
• Berechnetes Molekulargewicht: 730 aa, 81 kDa
• GenBank-Zugangsnummer: BC131585
• Gene symbol: SYTL5
• Gene ID (NCBI): 94122
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

SYTL5, also known as SLP5, is a member of the synaptotagmin-like protein (Slp) family. Members of this family are characterized by the presence of an N-terminal Slp homology domain (SHD), which functions as a Rab27-binding domain, and C-terminal tandem C2 domains, putative Ca(2+)-binding motifs. SYTL5 promotes the development and progression of papillary thyroid carcinoma (PTC) by activating the NF-κB signaling pathway (PMID: 36378561).