• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

Synaptotagmin-10 Polyklonaler Antikörper

Synaptotagmin-10 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 20881-1-PBS

Synonyme

SytX, SYT10, Synaptotagmin X

Filter:
  • Western Blot (WB) analysis of various lysates using Synaptotagmin-10 Polyclonal antibody (20881-1-AP)

    WB analysis using 20881-1-AP (same clone as 20881-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 20881-1-AP (SYT10 antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20881-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

20881-1-PBS bindet in WB, Indirect ELISA Synaptotagmin-10 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Synaptotagmin-10 fusion protein Ag15018
Vollständiger Name synaptotagmin X
Berechnetes Molekulargewicht 523 aa, 59 kDa
Beobachtetes Molekulargewicht70 kDa
GenBank-ZugangsnummerBC101024
Gene symbol Synaptotagmin-10
Gene ID (NCBI) 341359
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (PMID: 8058779). SYT10 (synaptotagmin-10) functions as a Ca2+ sensor to trigger IGF-1 exocytosis in neurons. Loss of Syt10 impairs activity-dependent IGF-1 secretion in olfactory bulb neurons and results in smaller neurons and an overall reduction in the number of synapses (PMID: 21496647).