Synaptotagmin-14 Polyklonaler Antikörper

Synaptotagmin-14 Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 20561-1-PBS

Synonyme

Synaptotagmin XIV, SYT14, SytXIV

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  WB analysis using 20561-1-AP (same clone as 20561-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 20561-1-AP (Synaptotagmin-14 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20561-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse cerebellum using 20561-1-AP (same clone as 20561-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 20561-1-AP (Synaptotagmin-14 antibody) at dilution of 1:300 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20561-1-PBS in a different storage buffer formulation.

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  IHC staining of mouse cerebellum using 20561-1-AP (same clone as 20561-1-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse cerebellum tissue slide using 20561-1-AP (Synaptotagmin-14 antibody) at dilution of 1:300 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 20561-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

20561-1-PBS bindet in WB, IHC, Indirect ELISA Synaptotagmin-14 und zeigt Reaktivität mit human, Maus, Ratten

• Getestete Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: synaptotagmin XIV
• Berechnetes Molekulargewicht: 62 kDa
• Beobachtetes Molekulargewicht: 62-65 kDa
• GenBank-Zugangsnummer: NM_153262
• Gene symbol: Synaptotagmin-14
• Gene ID (NCBI): 255928
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (PMID: 8058779). Synaptotagmin-14 (SYT14) is highly expressed in brain tissues. A homozygous mutation of SYT14 is involved in the pathogenesis of spinocerebellar ataxia (SCA) (PMID: 21835308).