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Synaptotagmin-3 Polyklonaler Antikörper

Synaptotagmin-3 Polyklonal Antikörper für WB, IHC, IF-P, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus, Ratte

Anwendung

WB, IHC, IF-P, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 28667-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of various lysates using Synaptotagmin-3 Polyclonal antibody (28667-1-AP)

    WB analysis using 28667-1-AP (same clone as 28667-1-PBS)

    mouse brain tissue and rat brain tissue were subjected to SDS PAGE followed by western blot with 28667-1-AP (Synaptotagmin-3 antibody) at dilution of 1:6000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 28667-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse brain tissue using Synaptotagmin-3 Polyclonal antibody (28667-1-AP)

    IHC staining of mouse brain using 28667-1-AP (same clone as 28667-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28667-1-AP (Synaptotagmin-3 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28667-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of mouse brain tissue using Synaptotagmin-3 Polyclonal antibody (28667-1-AP)

    IHC staining of mouse brain using 28667-1-AP (same clone as 28667-1-PBS)

    Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 28667-1-AP (Synaptotagmin-3 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 28667-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of mouse brain tissue using Synaptotagmin-3 Polyclonal antibody (28667-1-AP)

    IF Staining of mouse brain using 28667-1-AP (same clone as 28667-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using Synaptotagmin-3 antibody (28667-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). This data was developed using the same antibody clone with 28667-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

28667-1-PBS bindet in WB, IHC, IF-P, Indirect ELISA Synaptotagmin-3 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen Synaptotagmin-3 fusion protein Ag30027
Vollständiger Name synaptotagmin III
Berechnetes Molekulargewicht 590 aa, 63 kDa
Beobachtetes Molekulargewicht70-75 kDa
GenBank-ZugangsnummerBC028379
Gene symbol Synaptotagmin-3
Gene ID (NCBI) 84258
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

The synaptotagmins are integral membrane proteins of synaptic vesicles thought to serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis (PMID: 8058779). Synaptotagmin-3 (SYT3) is highly expressed in brain, adipose tissue, and heart (PMID: 30545844). Synaptotagmin-3 is highly enriched in synaptic plasma membranes (PMID: 10373432). It has been reported that synaptotagmin-3 internalizes AMPA receptors to depress synaptic strength and promote forgetting (PMID: 30545844).