TAC1 Polyklonaler Antikörper

TAC1 Polyklonal Antikörper für IF, IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus und mehr (1)

Anwendung

IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen

5

Kat-Nr. : 13839-1-AP

Synonyme

Hs.2563, Neuromedin L, NK2, NKA, NKNA, PPT, Protachykinin 1, Substance K Neuropeptide K, Substance P, SubstanceP, TAC1, TAC2, tachykinin, precursor 1, Tachykinin-1

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Galerie der Validierungsdaten

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  IHC staining of mouse brain using 13839-1-AP

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 13839-1-AP (TAC1 Antibody) at dilution of 1:200 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of mouse brain using 13839-1-AP

  Immunohistochemical analysis of paraffin-embedded mouse brain tissue slide using 13839-1-AP (TAC1 Antibody) at dilution of 1:200 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human pancreas using 13839-1-AP

  Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 13839-1-AP (TAC1 antibody) at dilution of 1:200 (under 10x lens).

• 

  IHC staining of human pancreas using 13839-1-AP

  Immunohistochemical analysis of paraffin-embedded human pancreas tissue slide using 13839-1-AP (TAC1 antibody) at dilution of 1:200 (under 40x lens).

• 

  IHC staining of human brain using 13839-1-AP

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 13839-1-AP (TAC1 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human brain using 13839-1-AP

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 13839-1-AP (TAC1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human brain using 13839-1-AP

  Immunohistochemical analysis of paraffin-embedded human brain tissue slide using 13839-1-AP (TAC1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human stomach using 13839-1-AP

  Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 13839-1-AP (TAC1 antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human stomach using 13839-1-AP

  Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 13839-1-AP (TAC1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IHC staining of human stomach using 13839-1-AP

  Immunohistochemical analysis of paraffin-embedded human stomach tissue slide using 13839-1-AP (TAC1 antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

• 

  IF Staining of mouse brain using 13839-1-AP

  Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using TAC1 antibody (13839-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

• 

  IF Staining of mouse brain using 13839-1-AP

  Immunofluorescent analysis of (4% PFA) fixed mouse brain tissue using TAC1 antibody (13839-1-AP) at dilution of 1:200 and CoraLite®488-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IHC: Maushirngewebe, humanes Hirngewebe, humanes Magengewebe, humanes Pankreasgewebe; Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.
• Erfolgreiche Detektion in IF: Maushirngewebe

Empfohlene Verdünnung

• Immunhistochemie (IHC): IHC : 1:50-1:500
• Immunfluoreszenz (IF): IF : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• IF: See 1 publications below

Produktinformation

13839-1-AP bindet in IHC, IF, ELISA TAC1 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human, Maus, Ratte
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: TAC1 fusion protein Ag4790
• Vollständiger Name: tachykinin, precursor 1
• Berechnetes Molekulargewicht: 129 aa, 15 kDa
• GenBank-Zugangsnummer: BC018047
• Gene symbol: TAC1
• Gene ID (NCBI): 6863
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS mit 0.02% Natriumazid und 50% Glycerin pH 7.3.
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

achykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.TAC1 is an abbreviation for protachykinin 1, a protein that is encoded by the TAC1 gene, which is responsible for 4 products of the tachykinin peptide hormone family: substance P, neurokinin A, and the related peptides, neuropeptideK and neuropeptide (PMID:21453958).This antibody is specific to TAC1.

Publikationen

Species	Application	Title
mouse		Front Cell Neurosci; Paralogs of the Calcium-Dependent Activator Protein for Secretion Differentially Regulate Synaptic Transmission and Peptide Secretion in Sensory Neurons.; Authors - Ali H Shaib
mouse		J Neuroimmunol; Tropisetron attenuates lipopolysaccharide induced neuroinflammation by inhibiting NF-κB and SP/NK1R signaling pathway.; Authors - Yan Yu
human		Biomed Chromatogr; A new method for detecting Na+ , K+ -ATPase activity by ICP-MS: Quantitative analysis on the inhibitory effect of rhein on Na+ , K+ -ATPase activity by ICP-MS in HCT116 cells.; Authors - Hui Dai
rat		Exp Lung Res; Capsaicin pretreatment reversed pulmonary arterial hypertension by alleviating inflammation via p38MAPK pathway.; Authors - Ying Xu
	IF	PLoS Genet; ZYG-9ch-TOG promotes the stability of acentrosomal poles via regulation of spindle microtubules in C. elegans oocyte meiosis; Authors - Gabriel Cavin-Meza

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