TNFRSF13B/CD267 Rekombinanter Antikörper
TNFRSF13B/CD267 Rekombinant Antikörper für WB, IF/ICC, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
Maus
Anwendung
WB, IF/ICC, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
250265D1
Kat-Nr. : 85902-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
85902-1-PBS bindet in WB, IF/ICC, Indirect ELISA TNFRSF13B/CD267 und zeigt Reaktivität mit Maus
| Getestete Reaktivität | Maus |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Rekombinant |
| Typ | Antikörper |
| Immunogen | TNFRSF13B/CD267 fusion protein Eg1814 |
| Vollständiger Name | tumor necrosis factor receptor superfamily, member 13b |
| Berechnetes Molekulargewicht | 27 kDa |
| Beobachtetes Molekulargewicht | 30-32 kDa |
| GenBank-Zugangsnummer | NM_021349.1 |
| Gene symbol | Tnfrsf13b |
| Gene ID (NCBI) | 57916 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Tumor necrosis factor receptor superfamily member 13B (TNFRSF13B), also known as CD267 or TACI, is a transmembrane protein of the TNF receptor superfamily found predominantly on B cells (PMID: 10920230). TACI is also expressed on activated T cells, myeloma cells, and expressed by monocytes intracellularly at a low level (PMID: 11429548; 16825497). TNFRSF13B is a receptor for TNFSF13/APRIL/CD256 and TNFSF13B/BAFF/CD257 and mediates calcineurin-dependent activation of NF-AT, as well as activation of NF-κB and AP-1 (PMID: 10956646; 10973284; 9311921). It is involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.



