TACSTD2/TROP2 Monoklonaler Antikörper
TACSTD2/TROP2 Monoklonal Antikörper für WB, IHC, IF/ICC, IF-P, Indirect ELISA
Wirt / Isotyp
Maus / IgG2b
Getestete Reaktivität
human, Maus
Anwendung
WB, IHC, IF/ICC, IF-P, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
5A6B1
Kat-Nr. : 68141-1-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
68141-1-PBS bindet in WB, IHC, IF/ICC, IF-P, Indirect ELISA TACSTD2/TROP2 und zeigt Reaktivität mit human, Maus
| Getestete Reaktivität | human, Maus | 
| Wirt / Isotyp | Maus / IgG2b | 
| Klonalität | Monoklonal | 
| Typ | Antikörper | 
| Immunogen | TACSTD2/TROP2 fusion protein Ag25775 | 
| Vollständiger Name | tumor-associated calcium signal transducer 2 | 
| Berechnetes Molekulargewicht | 36 kDa | 
| Beobachtetes Molekulargewicht | 40-50 kDa | 
| GenBank-Zugangsnummer | BC009409 | 
| Gene symbol | TROP2 | 
| Gene ID (NCBI) | 4070 | 
| Konjugation | Unkonjugiert | 
| Form | Liquid | 
| Reinigungsmethode | Protein-A-Reinigung | 
| Lagerungspuffer | PBS only | 
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. | 
Hintergrundinformationen
Trophoblast cell surface antigen 2 (TROP2), also named as TACSTD2, is a transmembrane glycoprotein. TROP2 plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. TROP2 is overexpressed in most carcinomas and is involved in cancer proliferation, migration, invasion, and metastasis. Congenital mutations of TROP2 cause a rare autosomal recessive disease which may lead to blindness-the gelatinous drop-like corneal disease (PMID: 35688908).











