TACSTD2/TROP2 Monoklonaler Antikörper

TACSTD2/TROP2 Monoklonal Antikörper für IF-P

Wirt / Isotyp

Maus / IgG2b

Getestete Reaktivität

human, Maus

Anwendung

IF-P

Konjugation

APC Fluorescent Dye

CloneNo.

5A6B1

Kat-Nr. : APC-68141

Synonyme

TACSTD2, GA733-1, GA733 1, GA733, EGP 1

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  IF Staining of mouse skin using APC-68141

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse skin tissue using APC TACSTD2/TROP2 antibody (APC-68141, Clone: 5A6B1 ) at dilution of 1:200. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IF Staining of mouse skin using APC-68141

  Immunofluorescent analysis of (4% PFA) fixed paraffin-embedded mouse skin tissue using APC TACSTD2/TROP2 antibody (APC-68141, Clone: 5A6B1 ) at dilution of 1:200. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IF-P: Maushautgewebe

Empfohlene Verdünnung

• Immunfluoreszenz (IF)-P: IF-P : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

APC-68141 bindet in IF-P TACSTD2/TROP2 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Maus / IgG2b
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: TACSTD2/TROP2 fusion protein Ag25775
• Vollständiger Name: tumor-associated calcium signal transducer 2
• Berechnetes Molekulargewicht: 36 kDa
• Beobachtetes Molekulargewicht: 40-50 kDa
• GenBank-Zugangsnummer: BC009409
• Gene symbol: TROP2
• Gene ID (NCBI): 4070
• Konjugation: APC Fluorescent Dye
• Excitation/Emission maxima wavelengths: 650 nm / 660 nm
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide and 0.5% BSA
• Lagerungsbedingungen: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Trophoblast cell surface antigen 2 (TROP2), also named as TACSTD2, is a transmembrane glycoprotein. TROP2 plays a role in transducing intracellular calcium signals. It is expressed in trophoblast cells, cornea and multi-stratified epithelia. TROP2 is overexpressed in most carcinomas and is involved in cancer proliferation, migration, invasion, and metastasis. Congenital mutations of TROP2 cause a rare autosomal recessive disease which may lead to blindness-the gelatinous drop-like corneal disease (PMID: 35688908).