TAF12 Monoklonaler Antikörper

TAF12 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

4E12D2

Kat-Nr. : 67621-1-PBS

Synonyme

4E12D2, TAF15, TAFII-20/TAFII-15

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  WB analysis using 67621-1-Ig (same clone as 67621-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 67621-1-Ig (TAF12 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67621-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

67621-1-PBS bindet in WB, Indirect ELISA TAF12 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: TAF12 fusion protein Ag16597
• Vollständiger Name: TAF12 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 20kDa
• Berechnetes Molekulargewicht: 18 kDa
• Beobachtetes Molekulargewicht: 21 kDa
• GenBank-Zugangsnummer: BC011986
• Gene symbol: TAF12
• Gene ID (NCBI): 6883
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TAF12, also named TAF15 or TAF2J, is a TBP-associated factor that is contained in Pol I- and Pol II-specific TBP-TAF complexes, it is also a component of the transcription factor IID (TFIID) complex, which is essential for mediating regulation of RNA polymerase transcription. TAF12 plays a key role in regulating eukaryotic gene expression by directly binding promoters and enhancer-bound transactivator proteins. Likewise, TAF12 recruits Gadd45a and the nucleotide excision repair complex to the promoter of rRNA genes leading to active DNA demethylation