TAF1B Polyklonaler Antikörper

TAF1B Polyklonal Antikörper für WB, IHC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 12818-1-PBS

Synonyme

RAF1B, RAFI63, RNA polymerase I-specific TBP-associated factor 63 kDa, SL1, TAFI63

---

• 

  WB analysis using 12818-1-AP (same clone as 12818-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 12818-1-AP (TAF1B antibody) at dilution of 1:1500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 12818-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 12818-1-AP (same clone as 12818-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 12818-1-AP (TAF1B antibody) at dilution of 1:200 (under 10x lens). This data was developed using the same antibody clone with 12818-1-PBS in a different storage buffer formulation.

• 

  IHC staining of human testis using 12818-1-AP (same clone as 12818-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human testis using 12818-1-AP (TAF1B antibody) at dilution of 1:200 (under 40x lens). This data was developed using the same antibody clone with 12818-1-PBS in a different storage buffer formulation.

---

Geprüfte Anwendungen

Produktinformation

12818-1-PBS bindet in WB, IHC, Indirect ELISA TAF1B und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: TAF1B fusion protein Ag3267
• Vollständiger Name: TATA box binding protein (TBP)-associated factor, RNA polymerase I, B, 63kDa
• Berechnetes Molekulargewicht: 588 aa, 69 kDa
• Beobachtetes Molekulargewicht: 69 kDa
• GenBank-Zugangsnummer: BC018137
• Gene symbol: TAF1B
• Gene ID (NCBI): 9014
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TAF1B is a component of the RNA polymerase I core factor complex that acts as a GTF2B/TFIIB-like factor and plays a key role in multiple steps during transcription initiation such as pre-initiation complex (PIC) assembly and postpolymerase recruitment events in polymerase I (Pol I) transcription. It binds to rDNA promoters and plays a role in Pol I recruitment as a component of the SL1/TIF-IB complex, and possibly directly through its interaction with RRN3 (PMID: 11250903; 11283244; 15970593; 21921199).