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TAX1BP1 Polyklonaler Antikörper

TAX1BP1 Polyklonal Antikörper für WB, IHC, IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

WB, IHC, IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 14424-1-PBS

Synonyme

TRAF6-binding protein, Tax1-binding protein 1, T6BP, PRO0105

Filter:
  • Western Blot (WB) analysis of various lysates using TAX1BP1 Polyclonal antibody (14424-1-AP)

    WB analysis using 14424-1-AP (same clone as 14424-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 14424-1-AP (TAX1BP1 antibody) at dilution of 1:2500 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 14424-1-PBS in a different storage buffer formulation.

  • Immunohistochemistry (IHC) staining of human skin cancer tissue using TAX1BP1 Polyclonal antibody (14424-1-AP)

    IHC staining of human skin cancer using 14424-1-AP (same clone as 14424-1-PBS)

    Immunohistochemical analysis of paraffin-embedded skin cancer slide using 14424-1-AP (TAX1BP1 antibody) at dilution of 1:500 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 14424-1-PBS in a different storage buffer formulation.

  • Immunofluorescence (IF) / fluorescent staining of HeLa cells using TAX1BP1 Polyclonal antibody (14424-1-AP)

    IF Staining of HeLa using 14424-1-AP (same clone as 14424-1-PBS)

    Immunofluorescent analysis of (-20°C Ethanol) fixed HeLa cells using TAX1BP1 antibody (14424-1-AP) at dilution of 1:400 and Multi-rAb CoraLite ® Plus 488-Goat Anti-Rabbit Recombinant Secondary Antibody (H+L) (RGAR002). This data was developed using the same antibody clone with 14424-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

14424-1-PBS bindet in WB, IHC, IF/ICC, Indirect ELISA TAX1BP1 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TAX1BP1 fusion protein Ag5789
Vollständiger Name Tax1 (human T-cell leukemia virus type I) binding protein 1
Berechnetes Molekulargewicht 91 kDa
Beobachtetes Molekulargewicht 90 kDa
GenBank-ZugangsnummerBC050358
Gene symbol TAX1BP1
Gene ID (NCBI) 8887
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5.