TAX1BP1 Monoklonaler Antikörper

TAX1BP1 Monoklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

1H2D10

Kat-Nr. : 60466-1-PBS

Synonyme

TRAF6-binding protein, Tax1-binding protein 1, T6BP, PRO0105, 1H2D10

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  WB analysis using 60466-1-Ig (same clone as 60466-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 60466-1-Ig (TAX1BP1 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60466-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

60466-1-PBS bindet in WB, Indirect ELISA TAX1BP1 und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Maus / IgG1
• Klonalität: Monoklonal
• Typ: Antikörper
• Immunogen: TAX1BP1 fusion protein Ag6279
• Vollständiger Name: Tax1 (human T-cell leukemia virus type I) binding protein 1
• Berechnetes Molekulargewicht: 91 kDa
• Beobachtetes Molekulargewicht: 68 kDa, 85 kDa
• GenBank-Zugangsnummer: BC050358
• Gene symbol: TAX1BP1
• Gene ID (NCBI): 8887
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-G-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TAX1BP1 (also named as T6BP and TXBP151) inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. It is degraded by caspase-3-like family proteins upon TNF-induced apoptosis. TAX1BP1 may also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. TAX1BP1 binds TRAF6 but not TRAFs 1-5. TAX1BP1 has 4 isoforms, this antibody recognizes both TXBP151-L and TXBP151-S.