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TBX21/T-bet Rekombinanter Antikörper

TBX21/T-bet Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

240849C1

Kat-Nr. : 83804-6-PBS

Synonyme

TBX21, TBX21,T-bet, TBX 21, T-box transcription factor TBX21, T-box protein 21

Filter:
  • Western Blot (WB) analysis of CTLL-2 cells using TBX21/T-bet Recombinant antibody (83804-6-RR)

    WB analysis of CTLL-2 using 83804-6-RR (same clone as 83804-6-PBS)

    CTLL-2 cells were subjected to SDS PAGE followed by western blot with 83804-6-RR (TBX21/T-bet antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83804-6-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83804-6-RR

    Affinity and Kinetic Characterization of 83804-6-RR

    Biolayer interferometry (BLl) kinetic assays of 83804-6-RR against Human TBX21,T-bet were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

83804-6-PBS bindet in WB, Indirect ELISA TBX21/T-bet und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen TBX21/T-bet fusion protein Ag4618
Vollständiger Name T-box 21
Berechnetes Molekulargewicht 535 aa, 58 kDa
Beobachtetes Molekulargewicht60-65 kDa
GenBank-ZugangsnummerBC039739
Gene symbol TBX21/T-bet
Gene ID (NCBI) 30009
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TBX21 is a transcription factor that drives the Th1 immune response primarily through promoting expression of the IFN-γ gene. TBX21 initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs. It has also been shown to play an influential role in inflammatory processes such as inflammatory bowel disease, autoimmune diseases such as rheumatoid arthritis, and immune-mediated conditions like asthma.