TBX21/T-bet Rekombinanter Antikörper

TBX21/T-bet Rekombinant Antikörper für WB, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, ELISA

Konjugation

Unkonjugiert

CloneNo.

240849C1

Kat-Nr. : 83804-6-RR

Synonyme

TBX21, TBX21,T-bet, TBX 21, T-box transcription factor TBX21, T-box protein 21

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  WB analysis of CTLL-2 using 83804-6-RR

  CTLL-2 cells were subjected to SDS PAGE followed by western blot with 83804-6-RR (TBX21/T-bet antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours.

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  Affinity and Kinetic Characterization of 83804-6-RR

  Biolayer interferometry (BLl) kinetic assays of 83804-6-RR against Human TBX21,T-bet were performed. The affinity constant is below 1 pM.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in WB: CTLL-2 cells

Empfohlene Verdünnung

• Western Blot (WB): WB : 1:5000-1:50000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Produktinformation

83804-6-RR bindet in WB, ELISA TBX21/T-bet und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: TBX21/T-bet fusion protein Ag4618
• Vollständiger Name: T-box 21
• Berechnetes Molekulargewicht: 535 aa, 58 kDa
• Beobachtetes Molekulargewicht: 60-65 kDa
• GenBank-Zugangsnummer: BC039739
• Gene symbol: TBX21/T-bet
• Gene ID (NCBI): 30009
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein A purfication
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TBX21 is a transcription factor that drives the Th1 immune response primarily through promoting expression of the IFN-γ gene. TBX21 initiates TH1 lineage development from naive TH precursor cells both by activating TH1 genetic programs and by repressing the opposing TH2 programs. It has also been shown to play an influential role in inflammatory processes such as inflammatory bowel disease, autoimmune diseases such as rheumatoid arthritis, and immune-mediated conditions like asthma.