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TBX4/5 Rekombinanter Antikörper

TBX4/5 Rekombinant Antikörper für IF/ICC, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

IF/ICC, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

242565F1

Kat-Nr. : 84997-4-PBS

Synonyme

TBX5, HOS, T box 5, T-box protein 5, T-box transcription factor TBX5

Filter:
  • Immunofluorescence (IF) / fluorescent staining of U2OS cells using TBX4/5 Recombinant antibody (84997-4-RR)

    IF Staining of U2OS using 84997-4-RR (same clone as 84997-4-PBS)

    Immunofluorescent analysis of (4% PFA) fixed U2OS cells using TBX5 antibody (84997-4-RR, Clone: 242565F1 ) at dilution of 1:800 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2), CL594-Phalloidin (red). This data was developed using the same antibody clone with 84997-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84997-4-RR

    Affinity and Kinetic Characterization of 84997-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84997-4-RR against Human TBX4/5 were performed. The affinity constant is 37.3 nM.

Geprüfte Anwendungen

Produktinformation

84997-4-PBS bindet in IF/ICC, Indirect ELISA TBX4/5 und zeigt Reaktivität mit human

Getestete Reaktivität human
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen TBX4/5 fusion protein Ag3845
Vollständiger Name T-box 5
Berechnetes Molekulargewicht 518 aa, 57 kDa
GenBank-ZugangsnummerBC027942
Gene symbol TBX5
Gene ID (NCBI) 6910
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-A-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

T-box genes encode a family of transcription factors that have been identified in all metazoans and which play diverse roles during embryonic development. TBX5, a member of T-box family, has an essential role in the initiation of limb outgrowth and heart development. Genetic variation near TBX5 that associates with PR and/or QRS interval variation, which suggests that TBX5 plays a role in CCS function in the general population. Because 77 % amino acid sequence of TBX5 is identical to TBX4, this antibody recognizes both TBX4 and TBX5.