• All
  • Primary Antibodies
  • Conjugated Antibodies for IF
  • Conjugated Antibodies for FC
  • Secondary Antibodies
  • Antibody Labeling KitsNew
  • ELISA Kits
  • IHC Kits
  • Magnetic Cell Separation Kits
  • Cytokines & Growth Factors
  • Neutralizing/activating Antibodies
  • Nanobody-based Reagents
  • Accessory Products and Kits
  • Fusion Proteins
×
×
Host
0
Species Reactivity
0
Species Reactivity
0
Conjugate
0
Conjugate
0
Compatible Species
0
Conjugate
0

TCF1/TCF7 Rekombinanter Antikörper

TCF1/TCF7 Rekombinant Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

CloneNo.

241154D2

Kat-Nr. : 84089-4-PBS

Synonyme

TCF7, 241154D2, T cell factor 1, TCF 1, TCF 7

Filter:
  • Western Blot (WB) analysis of various lysates using TCF1/TCF7 Recombinant antibody (84089-4-RR)

    WB analysis using 84089-4-RR (same clone as 84089-4-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 84089-4-RR (TCF7 antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84089-4-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84089-4-RR

    Affinity and Kinetic Characterization of 84089-4-RR

    Biolayer interferometry (BLl) kinetic assays of 84089-4-RR against Human TCF1/TCF7 were performed. The affinity constant is below 1 pM.

Geprüfte Anwendungen

Produktinformation

84089-4-PBS bindet in WB, Indirect ELISA TCF1/TCF7 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Rekombinant
Typ Antikörper
Immunogen TCF1/TCF7 fusion protein Ag5792
Vollständiger Name transcription factor 7 (T-cell specific, HMG-box)
Berechnetes Molekulargewicht 42 kDa
Beobachtetes Molekulargewicht 58 kDa
GenBank-ZugangsnummerBC048769
Gene symbol TCF1/TCF7
Gene ID (NCBI) 6932
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein A purfication
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TCF7, also known as TCF1, belongs to the TCF/LEF family. TCF7 is part of the Wnt signaling pathway and plays an important role in the differentiation and self-renewal of memory T cells. It has been found that TCF7 is necessary to revive T cells in response to PD-1 blockade against viral infection or cancer. TCF7 is mainly expressed in T-cells and is also detected in proliferating intestinal epithelial cells and in the basal epithelial cells of mammary gland epithelium. TCF7 has 16 isoforms with the molecular mass of 28-54 kDa (PMID: 34044317).