TCR Vγ5Vδ1 Rekombinanter Antikörper

TCR Vγ5Vδ1 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

251677A1

Kat-Nr. : 98527-1-RR

Synonyme

TCR gamma delta, Vγ5Vδ1

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  FC experiment of human PBMCs using 98527-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-TCR Vγ5Vδ1 Rabbit RecAb (98527-1-RR, Clone:251677A1) , or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD3. Cells were not fixed. Lymphocytes were gated.

• 

  FC experiment of human PBMCs using 98527-1-RR

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-TCR Vγ5Vδ1 Rabbit RecAb (98527-1-RR, Clone:251677A1)(red) , or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9)(blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Lymphocytes were gated.

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Geprüfte Anwendungen

• Erfolgreiche Detektion in FC: humane PBMCs

Empfohlene Verdünnung

Anwendung	Verdünnung
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Produktinformation

98527-1-RR bindet in FC TCR Vγ5Vδ1 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: TCR Vγ5Vδ1
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS with 0.09% sodium azide
• Lagerungsbedingungen: Store at 2 - 8°C. Stable for one year after shipment.

Hintergrundinformationen

TCR Vγ5Vδ1 refers to a specific type of T cell receptor (TCR) found on γδ T cells. These cells are a distinct subset of T lymphocytes that play a role in immune responses, particularly in maintaining tissue integrity and responding to stress signals. The Vγ5Vδ1 TCR is uniquely expressed on a population of T cells called dendritic epidermal T cells (DETCs) that reside in the epidermis (PMID: 35260830, 35031803). The Vγ5Vδ1 TCR-CD3 complex forms an asymmetric dimer, with the Vγ5 domains of each protomer interacting to create a back-to-back structure. This dimeric form is essential for T cell activation (PMID: 38657677).