TCR Vγ9Vδ2 Rekombinanter Antikörper

TCR Vγ9Vδ2 Rekombinant Antikörper für FC

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

251678A1

Kat-Nr. : 98526-1-PBS

Synonyme

TCR gamma delta, Vγ9Vδ2

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  FC experiment of human PBMCs using 98526-1-RR (same clone as 98526-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-TCR Vγ9Vδ2 Rabbit RecAb (98526-1-RR, Clone:251678A1), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Human CD3. Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98526-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98526-1-RR (same clone as 98526-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-TCR Vγ9Vδ2 Rabbit RecAb (98526-1-RR, Clone:251678A1)(red), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9)(blue) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98526-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

98526-1-PBS bindet in FC TCR Vγ9Vδ2 und zeigt Reaktivität mit human

• Getestete Reaktivität: human
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: Rekombinantes Protein
• Vollständiger Name: TCR Vγ9Vδ2
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

TCR Vγ9Vδ2 refers to a specific type of T cell receptor (TCR) found on a subset of gamma delta (γδ) T cells called Vγ9Vδ2 T cells. These cells are a major population of human γδ T cells in the blood and are characterized by the expression of a unique TCR that recognizes phosphoantigens (pAg). Vγ9Vδ2 T cell activation is tightly regulated by a variety of activating or inhibitory receptors which are specific for constitutively expressed or stress-modulated ligands (PMID: 20447835, 40040716). The most effective TCR Vg9Vd2-mediated cell activation relies on TCR interaction with BTN3A1, BTN3A2, and BTN2A1 molecules expressed by target cells (PMID: 25566259).