TCR beta Rekombinanter Antikörper

TCR beta Rekombinant Antikörper für FC

Wirt / Isotyp

hamster / IgG2a

Getestete Reaktivität

Maus

Anwendung

FC

Konjugation

Unkonjugiert

CloneNo.

H57-597

Kat-Nr. : 65678-1-PBS

Synonyme

Tcrb, T cell receptor beta chain, TCRβ, Tib

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  FC experiment of mouse splenocytes using 65678-1-AR (same clone as 65678-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.5 ug Anti-Mouse TCR beta Hamster IgG2a RecAb (65678-1-AR, Clone: H57-597) or Armenian Hamster IgG Isotype Control (PIP) (65210-1-Ig, Clone: PIP), and FITC-conjugated Anti-Armenian Hamster IgG antibody. Cells were co-stained with CoraLite® Plus 647 Anti-Mouse CD3. Cells were not fixed. This data was developed using the same antibody clone with 65678-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse splenocytes using 65678-1-AR (same clone as 65678-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.5 ug Anti-Mouse TCR beta Hamster IgG2a RecAb (65678-1-AR, Clone: H57-597) (red) or Armenian Hamster IgG Isotype Control (PIP) (65210-1-Ig, Clone: PIP) (blue), and FITC-conjugated Anti-Armenian Hamster IgG antibody. Cells were not fixed. This data was developed using the same antibody clone with 65678-1-PBS in a different storage buffer formulation.

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Geprüfte Anwendungen

Produktinformation

65678-1-PBS bindet in FC TCR beta und zeigt Reaktivität mit Maus

• Getestete Reaktivität: Maus
• Wirt / Isotyp: hamster / IgG2a
• Klonalität: Rekombinant
• Typ: Antikörper
• Immunogen: k.A.
• Vollständiger Name: T-cell receptor beta chain
• Gene symbol: TCR beta
• Gene ID (NCBI): 21577
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Protein-A-Reinigung
• Lagerungspuffer: PBS only
• Lagerungsbedingungen: Store at -80°C.

Hintergrundinformationen

T-cell receptor (TCR) consists of heterodimeric glycoproteins (TCR alpha/beta or gamma/delta) that demonstrate homology with immunoglobulins (PMID: 2144901). TCR beta is a member of the immunoglobulin superfamily and is expressed on alpha/beta TCR-bearing T cells and thymocytes. The TCR heterodimers are noncovalently associated with CD3. The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta (PMID: 1826255). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).