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TEAD2 Polyklonaler Antikörper

TEAD2 Polyklonal Antikörper für WB, Indirect ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, Indirect ELISA

Konjugation

Unkonjugiert

Kat-Nr. : 21159-1-PBS

Synonyme

Filter:
  • Western Blot (WB) analysis of mouse colon tissue using TEAD2 Polyclonal antibody (21159-1-AP)

    WB analysis of mouse colon using 21159-1-AP (same clone as 21159-1-PBS)

    mouse colon tissue were subjected to SDS PAGE followed by western blot with 21159-1-AP (TEAD2 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21159-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of mouse lung tissue using TEAD2 Polyclonal antibody (21159-1-AP)

    WB analysis of mouse lung using 21159-1-AP (same clone as 21159-1-PBS)

    mouse lung tissue were subjected to SDS PAGE followed by western blot with 21159-1-AP (TEAD2 Antibody) at dilution of 1:300 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 21159-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

21159-1-PBS bindet in WB, Indirect ELISA TEAD2 und zeigt Reaktivität mit human, Maus

Getestete Reaktivität human, Maus
Wirt / Isotyp Kaninchen / IgG
Klonalität Polyklonal
Typ Antikörper
Immunogen TEAD2 fusion protein Ag14074
Vollständiger Name TEA domain family member 2
Berechnetes Molekulargewicht 447 aa, 49 kDa
Beobachtetes Molekulargewicht 55-65 kDa
GenBank-ZugangsnummerBC051301
Gene symbol TEAD2
Gene ID (NCBI) 8463
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Antigen-Affinitätsreinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

TEAD2 belongs to a protein family that shares the TEA/ATTS domain. It acts as a transcriptional factor by cooperatively binding to the GT-IIC and Sph(I 1 II) enhansons in the simian virus 40 (SV40) enhancer. Also, it can modulate SV40 late transcription together with a large T antigen. The transcriptional activity of TEAD2 required several regions of the proteins, TBP-associated factors, and limiting transcriptional intermediary factors. TEAD2 also performs an essential role in the Hippo signaling pathway. TEAD2 regulates gene expression of YAP1 and WWTR1/TAZ, thus mediating cell proliferation, migration, and epithelial-mesenchymal transition induction. TEAD2 is strongly expressed in the human ovarian carcinoma cell line.