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TERF1 Monoklonaler Antikörper

TERF1 Monoklonal Antikörper für Indirect ELISA, WB

Wirt / Isotyp

Maus / IgG1

Getestete Reaktivität

human, Maus, Ratte

Anwendung

Indirect ELISA, WB

Konjugation

Unkonjugiert

CloneNo.

1D10G4

Kat-Nr. : 67592-1-PBS

Synonyme

Telomeric repeat-binding factor 1, t TRF1, PIN2, NIMA-interacting protein 2, hTRF1 AS

Filter:
  • Western Blot (WB) analysis of K-562 cells using TERF1 Monoclonal antibody (67592-1-Ig)

    WB analysis of K-562 using 67592-1-Ig (same clone as 67592-1-PBS)

    K-562 cells were subjected to SDS PAGE followed by western blot with 67592-1-Ig (TERF1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67592-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of HEK-293 cells using TERF1 Monoclonal antibody (67592-1-Ig)

    WB analysis of HEK-293 using 67592-1-Ig (same clone as 67592-1-PBS)

    HEK-293 cells were subjected to SDS PAGE followed by western blot with 67592-1-Ig (TERF1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67592-1-PBS in a different storage buffer formulation.

  • Western Blot (WB) analysis of Jurkat cells using TERF1 Monoclonal antibody (67592-1-Ig)

    WB analysis of Jurkat using 67592-1-Ig (same clone as 67592-1-PBS)

    Jurkat cells were subjected to SDS PAGE followed by western blot with 67592-1-Ig (TERF1 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67592-1-PBS in a different storage buffer formulation.

Geprüfte Anwendungen

Produktinformation

67592-1-PBS bindet in Indirect ELISA, WB TERF1 und zeigt Reaktivität mit human, Maus, Ratten

Getestete Reaktivität human, Maus, Ratte
Wirt / Isotyp Maus / IgG1
Klonalität Monoklonal
Typ Antikörper
Immunogen TERF1 fusion protein Ag12540
Vollständiger Name telomeric repeat binding factor (NIMA-interacting) 1
Berechnetes Molekulargewicht 439 aa, 50 kDa
Beobachtetes Molekulargewicht 48-50 kDa
GenBank-ZugangsnummerBC029378
Gene symbol TERF1
Gene ID (NCBI) 7013
Konjugation Unkonjugiert
Form Liquid
Reinigungsmethode Protein-G-Reinigung
Lagerungspuffer PBS only
LagerungsbedingungenStore at -80°C. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

Telomeres are nucleoprotein complexes located at chromosome ends that consist of tandem arrays of TTAGGG repeats bound to specific proteins. Telomeres protect chromosome ends from degradation and end-to-end fusions, prevent activation of DNA damage checkpoints, and modulate the maintenance of telomeric DNA by telomerase. TERF1 (telomeric repeat-binding factor 1) binds the telomeric double-stranded TTAGGG repeat and negatively regulates telomere length. It's one component of the shelterin complex, which involved in the regulation of telomere length and protection.