TFDP2 Polyklonaler Antikörper
TFDP2 Polyklonal Antikörper für WB, IP, ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human, Maus
Anwendung
WB, IHC, IP, ELISA
Konjugation
Unkonjugiert
Kat-Nr. : 11500-1-AP
Synonyme
Geprüfte Anwendungen
| Erfolgreiche Detektion in WB | Mausherzgewebe, humanes Hirngewebe | 
| Erfolgreiche IP | SH-SY5Y-Zellen | 
Empfohlene Verdünnung
| Anwendung | Verdünnung | 
|---|---|
| Western Blot (WB) | WB : 1:500-1:1000 | 
| Immunpräzipitation (IP) | IP : 0.5-4.0 ug for 1.0-3.0 mg of total protein lysate | 
| It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Veröffentlichte Anwendungen
| WB | See 2 publications below | 
| IHC | See 1 publications below | 
Produktinformation
11500-1-AP bindet in WB, IHC, IP, ELISA TFDP2 und zeigt Reaktivität mit human, Maus
| Getestete Reaktivität | human, Maus | 
| In Publikationen genannte Reaktivität | human, Maus | 
| Wirt / Isotyp | Kaninchen / IgG | 
| Klonalität | Polyklonal | 
| Typ | Antikörper | 
| Immunogen | TFDP2 fusion protein Ag2054 | 
| Vollständiger Name | transcription factor Dp-2 (E2F dimerization partner 2) | 
| Berechnetes Molekulargewicht | 446 aa, 49 kDa | 
| Beobachtetes Molekulargewicht | 49 kDa | 
| GenBank-Zugangsnummer | BC021113 | 
| Gene symbol | TFDP2 | 
| Gene ID (NCBI) | 7029 | 
| Konjugation | Unkonjugiert | 
| Form | Liquid | 
| Reinigungsmethode | Antigen-Affinitätsreinigung | 
| Lagerungspuffer | PBS with 0.02% sodium azide and 50% glycerol | 
| Lagerungsbedingungen | Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA. | 
Hintergrundinformationen
TFDP2, also known as E2FDP2, is a coactivator of E2F factors and involves in EGF or IFN-gamma-mediated effects by enhancing or reducing active heterodimeric complexes. The DP2/E2F complex functions in the control of cell-cycle progression from G1 to S phase. The E2F1/DP complex appears to mediate both cell proliferation and apoptosis [PMID:16360038]. Binds DNA cooperatively with E2F family members through the E2 recognition site, 5'-TTTC[CG]CGC-3', found in the promoter region of a number of genes whose products are involved in cell cycle regulation or in DNA replication [PMID:16721044].
Protokolle
| PRODUKTSPEZIFISCHE PROTOKOLLE | |
|---|---|
| WB protocol for TFDP2 antibody 11500-1-AP | Protokoll herunterladen | 
| IP protocol for TFDP2 antibody 11500-1-AP | Protokoll herunterladen | 
| STANDARD-PROTOKOLLE | |
|---|---|
| Klicken Sie hier, um unsere Standardprotokolle anzuzeigen | 
Publikationen
| Species | Application | Title | 
|---|---|---|
| Mol Syst Biol The MHC I immunopeptidome conveys to the cell surface an integrative view of cellular regulation. | ||
| Front Mol Biosci Comprehensive analysis of senescence-related genes and immune infiltration in intervertebral disc degeneration: a meta-data approach utilizing bulk and single-cell RNA sequencing data | ||
| Neuropharmacology The Novel miR_146-Tfdp2 Axis Antagonizes METH-Induced Neuron Apoptosis and Cell Cycle Abnormalities in Tree Shrew | 




