TFPI Rekombinanter Antikörper
TFPI Rekombinant Antikörper für Cytometric bead array, Indirect ELISA
Wirt / Isotyp
Kaninchen / IgG
Getestete Reaktivität
human
Anwendung
Cytometric bead array, Indirect ELISA
Konjugation
Unkonjugiert
CloneNo.
240977F12
Kat-Nr. : 83838-4-PBS
Synonyme
Geprüfte Anwendungen
Produktinformation
83838-4-PBS bindet in Cytometric bead array, Indirect ELISA TFPI und zeigt Reaktivität mit human
| Getestete Reaktivität | human |
| Wirt / Isotyp | Kaninchen / IgG |
| Klonalität | Rekombinant |
| Typ | Antikörper |
| Immunogen | TFPI fusion protein Eg0855 |
| Vollständiger Name | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) |
| Berechnetes Molekulargewicht | 35 kDa |
| Beobachtetes Molekulargewicht | 40-45 kDa |
| GenBank-Zugangsnummer | NM_006287.6 |
| Gene symbol | TFPI |
| Gene ID (NCBI) | 7035 |
| Konjugation | Unkonjugiert |
| Form | Liquid |
| Reinigungsmethode | Protein-A-Reinigung |
| Lagerungspuffer | PBS only |
| Lagerungsbedingungen | Store at -80°C. 20ul Größen enthalten 0,1% BSA. |
Hintergrundinformationen
Tissue factor pathway inhibitor (TFPI) is a critical anticoagulant protein present in endothelium and platelets. TFPI is produced as two major isoforms in humans, TFPIa and TFPIb that result from alternative splicing. The TFPIb isoform localizes to the endothelium surface where it is a potent inhibitor of tissue factor-factor VIIa complexes that initiate blood coagulation. The TFPIa isoform is present in platelets. TFPI is a Kunitz-type serine protease inhibitor that exerts anticoagulant activity by blocking early procoagulant stimulia. TFPI can enhance anti-thrombotic treatment in sepsis, inflammatory diseases, and cardiovascular diseases.
