Thrombospondin 3-Specific Polyklonaler Antikörper

• Featured Product
• KD/KO Validated

Thrombospondin 3-Specific Polyklonal Antikörper für IHC, ELISA

Wirt / Isotyp

Kaninchen / IgG

Getestete Reaktivität

human, Maus

Anwendung

WB, IHC, IF, ELISA

Konjugation

Unkonjugiert

Publikationen(4)

Kat-Nr. : 19727-1-AP

Synonyme

THBS3, thrombospondin 3, Thrombospondin 3-Specific, TSP3

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  IHC staining of human liver using 19727-1-AP

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 19727-1-AP (Thrombospondin 3-Specific antibody) at dilution of 1:200 (under 10x lens).

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  IHC staining of human liver using 19727-1-AP

  Immunohistochemical analysis of paraffin-embedded human liver tissue slide using 19727-1-AP (Thrombospondin 3-Specific antibody) at dilution of 1:200 (under 40x lens).

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  IHC staining of mouse kidney using 19727-1-AP

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 19727-1-AP (Thrombospondin 3-Specific antibody) at dilution of 1:200 (under 10x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of mouse kidney using 19727-1-AP

  Immunohistochemical analysis of paraffin-embedded mouse kidney tissue slide using 19727-1-AP (Thrombospondin 3-Specific antibody) at dilution of 1:200 (under 40x lens. Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0).

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  IHC staining of human colon using 19727-1-AP

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 19727-1-AP (Thrombospondin 3-Specific antibody) at dilution of 1:200 (under 10x lens).

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  IHC staining of human colon using 19727-1-AP

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 19727-1-AP (Thrombospondin 3-Specific antibody) at dilution of 1:200 (under 40x lens).

• 

  IHC staining of human colon using 19727-1-AP

  Immunohistochemical analysis of paraffin-embedded human colon tissue slide using 19727-1-AP (Thrombospondin 3-Specific antibody) at dilution of 1:200 (under 40x lens).

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Geprüfte Anwendungen

• Erfolgreiche Detektion in IHC: humanes Lebergewebe, humanes Kolongewebe, Mausnierengewebe; Hinweis: Antigendemaskierung mit TE-Puffer pH 9,0 empfohlen. (*) Wahlweise kann die Antigendemaskierung auch mit Citratpuffer pH 6,0 erfolgen.

Empfohlene Verdünnung

• Immunhistochemie (IHC): IHC : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Veröffentlichte Anwendungen

• KD/KO: See 1 publications below
• WB: See 3 publications below
• IF: See 2 publications below

Produktinformation

19727-1-AP bindet in WB, IHC, IF, ELISA Thrombospondin 3-Specific und zeigt Reaktivität mit human, Maus

• Getestete Reaktivität: human, Maus
• In Publikationen genannte Reaktivität: human, Maus
• Wirt / Isotyp: Kaninchen / IgG
• Klonalität: Polyklonal
• Typ: Antikörper
• Immunogen: Peptid
• Vollständiger Name: thrombospondin 3
• Berechnetes Molekulargewicht: 104 kDa
• GenBank-Zugangsnummer: NM_007112
• Gene symbol: Thrombospondin 3
• Gene ID (NCBI): 7059
• Konjugation: Unkonjugiert
• Form: Liquid
• Reinigungsmethode: Antigen-Affinitätsreinigung
• Lagerungspuffer: PBS with 0.02% sodium azide and 50% glycerol
• Lagerungsbedingungen: Bei -20°C lagern. Nach dem Versand ein Jahr lang stabil Aliquotieren ist bei -20^oC Lagerung nicht notwendig. 20ul Größen enthalten 0,1% BSA.

Hintergrundinformationen

THBS3, also named as TSP3, belongs to the thrombospondin family. THBS3 is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. THBS3 can bind to fibrinogen, fibronectin, laminin and type V collagen. The antibody is specific to THBS3.

Publikationen

Species	Application	Title
mouse	WB	Nat Commun; Thbs1 induces lethal cardiac atrophy through PERK-ATF4 regulated autophagy.; Authors - Davy Vanhoutte
human	IF	Front Cell Dev Biol; Time-Resolved Extracellular Matrix Atlas of the Developing Human Skin Dermis.; Authors - Mansheng Li
mouse	WB	Mol Cell Biochem; Microrna363-5p targets thrombospondin3 to regulate pathological cardiac remodeling; Authors - Yu-Kun Ma
mouse	WB,IF	Nat Commun; Thrombospondin-3 augments injury-induced cardiomyopathy by intracellular integrin inhibition and sarcolemmal instability.; Authors - Tobias G Schips ; KO Validated